Claudia Rodríguez Almazán received her B. Sc. in Biology from the Faculty of Sciencies, UNAM (1997). M Sc from the Institute of Marine Sciencees and Limnology (2001): sea anemone pore-forming toxins. She carried out her graduate work in PhD in Biomedical Sciences (2007) from the Institute of Cell Physiology, UNAM, in physicochemical, thermodynamics of protein folding and stability. Postdoctoral stay at the Institute of Biotechnology, UNAM (2008-2010) in bacterial pore-forming toxins. Since 2010-2020, associated researcher at the Institute of Biotechnology, UNAM, in the areas: mechanism of action of pore-forming toxins and engineering of metalloenzyme proteins with application in biotechnology, nanotechnology biomedicine. Currently associated researcher at the Institute of Applied Sciences and Technology, UNAM. Distinctions: PRIDE C, SNI I, member of the Mexican Society of Biochemistry, Mexican Society of Biotechnology and Bioengineering, The Protein Society-USA. Tutor of the Postgraduate course in Biochemical Sciences, UNAM.  Tutor of undergraduate, master and doctoral students. Participation in 21 postgraduate courses. Publications in indexed journals. Technical project manager for CONACYT, DGAPA-PAPIIT, The Protein Society.

• Protein engineering for biosensor design.

• Physicochemical, thermodynamics of protein folding and stability.

• Mechanism of action of pore-forming toxins and their application in nanotechnology.

• Identification of potential actinoporins for the design of an immunotoxin with application in cancer therapy.
• Directed evolution and engineering of bacterial laccase proteins to obtain variants to optimize their activity.
• Venomic sea anemones.

• Participation in graduate level courses.
• Undergraduate/graduate thesis advising and professional practice supervision, advisory committees.

Graduate

Doctoral:

• Beatriz Miranda Zaragoza

Undegraduate

• Sandra Irene Salazar García

• Ramírez-Carreto S., Miranda-Zaragoza B., Rodríguez-Almazán C. Actinoporins: from the structure and function to the generation of biotechnological and therapeutic tools. Biomolecules 2020, 10, 539-557
• Cifuentes-Castro, V., Rodríguez-Almazán C., Silva-Sánchez J., Rudiño-Piñera E. The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site. Biochemical and Biophysical Research Communications, 2020, 522, 545-551.
• Ramíez-Carreto S., Vera-Estrella R., Portillo-Bobadilla T., Licea-Navarro A., Bernaldez-Sarabia J., Rudiño-Piñera, E., Verleyen J.J., Rodríguez E., Rodríguez-Almazán C. Proteomic and Transcriptomic Analysis of Anthopleura dowii Verrill (1869) Venom from Tentacles and Mucus. Mar Drugs. 2019 Jul 25;17(8). pii: E436. doi: 10.3390/md17080436.
• Ramirez-Carreto,S. Perez-Garcia,E.I. Salazar-Garcia,S.I. Bernaldez-Sarabia,J. LiceaNavarro,A. Rudino-Pinera,E. Perez-Martinez,L. Pedraza-Alva,G. RodríguezAlmazán,C. 2019. Identification of a pore-forming protein from sea anemone Anthopleura dowii Verrill (1869) venom by mass spectrometry Journal of Venomous Animals and Toxins Including Tropical Diseases, Feb 11;25:e147418. doi: 10.1590/1678-9199-JVATITD-1474-18. eCollection 2019.
• Jorge-Tonatiuh Ayala-Sumuano, Itzel amaro, Enrique Rudiño-Piñera, Alexei Licea-Navarro, Estefanía Rodríguez, Claudia Rodríguez Almazán. (2017). Sequenceng and de novo transcriptome assembly of Anthopleura dowii Verrill (1869), from Mexico. Genomics Data, 11, 92-94
• Hugo Serrano-Posada, Sara Centeno-Lejía, Sonia Patricia Rojas-Trejo, Claudia RodríguezAlmazán, Vivian Stojanoff and Enrique Rudiño-Piñera. 2015. X-ray-induced catalytic activesitereduction of a multicopper oxidase: structural insights into the proton-relay mechanism and O2 – reduction states. Acta Cryst. D71:2396-2411.
• Soberón M, Rodríguez Almazán, C., Muñoz-Garay,C., Pardo López, L., Porta, H. Bravo A.2013. Bacillus thuringiensis Cry and Cyt mutants useful to counter toxin action in specific environments and to overcome insect resistance in the field. Pesticide Biochemistry and Physiology, 104, 11-117.
• Bravo, A., Gómez I, Porta, H, García-Gómez B. I., Rodríguez Almazán, C. Pardo, L. Soberón, M. 2012. Evolution of Bacillus thuringiensis Cry toxins insecticidal activity. Microb. Biotechnol. 6: 17-26
• Rodriguez-Almazan,C. Reyes,E.Z. Zuniga-Navarrete,F. Munoz-Garay,C. Gomez,I., Evans,A.M. Likitvivatavanong,S. Bravo,A. Gill,S.S.Soberon,M. 2012. Cadherin binding is not a limiting step for Bacillus thuringiensis subs. israelensis Cry4Ba toxicity to Aedes aegypti larvae Biochem J, 443,711 717.
• Daniela Carmona, Claudia Rodríguez-Almazán, Carlos MuñozGaray, Leivi Portugal, Claudia Pérez, Ruud A. de Maagd, Petra Bakker, Mario Soberón, Alejandra Bravo. 2011 Dominant negative phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba mutants suggest heterooligomer formation among different Cry toxins. PLoS ONE, 6, e19952

• Ramírez-Carreto S., Miranda-Zaragoza B., Rodríguez-Almazán C. Actinoporins: from the structure and function to the generation of biotechnological and therapeutic tools. Biomolecules 2020, 10, 539-557

• Ramíez-Carreto S., Vera-Estrella R., Portillo-Bobadilla T., Licea-Navarro A., Bernaldez-Sarabia J., Rudiño-Piñera, E., Verleyen J.J., Rodríguez E., Rodríguez-Almazán C. Proteomic and Transcriptomic Analysis of Anthopleura dowii Verrill (1869) Venom from Tentacles and Mucus. Mar Drugs. 2019 Jul 25;17(8). pii: E436. doi: 10.3390/md17080436.

• Ramirez-Carreto,S. Perez-Garcia,E.I. Salazar-Garcia,S.I. Bernaldez-Sarabia,J. LiceaNavarro,A. Rudino-Pinera,E. Perez-Martinez,L. Pedraza-Alva,G. RodríguezAlmazán,C. 2019. Identification of a pore-forming protein from sea anemone Anthopleura dowii Verrill (1869) venom by mass spectrometry Journal of Venomous Animals and Toxins Including Tropical Diseases, Feb 11;25:e147418. doi: 10.1590/1678-9199-JVATITD-1474-18. eCollection 2019.

• Jorge-Tonatiuh Ayala-Sumuano, Itzel amaro, Enrique Rudiño-Piñera, Alexei Licea-Navarro, Estefanía Rodríguez, Claudia Rodríguez Almazán. (2017). Sequenceng and de novo transcriptome assembly of Anthopleura dowii Verrill (1869), from Mexico. Genomics Data, 11, 92-94

• Bravo, A., Gómez I, Porta, H, García-Gómez B. I., Rodríguez Almazán, C. Pardo, L. Soberón, M. 2012. Evolution of Bacillus thuringiensis Cry toxins insecticidal activity. Microb. Biotechnol. 6: 17-26.

• Rodriguez-Almazan,C. Reyes,E.Z. Zuniga-Navarrete,F. Munoz-Garay,C. Gomez,I., Evans,A.M. Likitvivatavanong,S. Bravo,A. Gill,S.S.Soberon,M. 2012. Cadherin binding is not a limiting step for Bacillus thuringiensis subs. israelensis Cry4Ba toxicity to Aedes aegypti larvae Biochem J, 443,711 717.

• Rodríguez Almazán,C. Arreola R, Rodríguez-Larrea D, Aguirre-López B, de Gómez-Puyou MT, PerezMontfort,R. GomezPuyou, A., Torres-Larios A. Structural basis of human triosephosphate isomerase defiency: mutation E104D is relatd to alterations of a conserved water network at the dimer interface.J. Biol Chem. 2008, 283 (34): 23254-63.

• Rodríguez-Almazán,C. Torner,F.J. Costas,M. PerezMontfort,R. de GomezPuyou,M.T. Puyou,A.G. 2007. The stability and formation of native proteins from unfolded monomers is increased through interactions with unrelated proteins PLoS ONE. 2 e497.